how long do venofer side effects last

If you do breastfeed while youre taking Injectafer, the drugs manufacturer recommends that you monitor your child for side effects of the drug. This gives a total cumulative dose of 1,500 mg of Injectafer. Usually, but not always, the bigger a person is the slower it takes for drugs to break down and leave the body. Serious side effects should be reported to a physician and/or PharmD for medical advice. In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). They can tell you about other medications that may work well for you. Last updated on Feb 20, 2023. All rights reserved. other treatments you receive, you will need to go back for several treatments with Venofer. WebMD does not provide medical advice, diagnosis or treatment. Keep all medications away from children and pets. It is very important that your doctor check you closely while you are receiving this medicine. Hypophosphatemia seems to mostly occur in people who are already at risk for low phosphorus levels. % As with all medications, the cost of Injectafer can vary. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. But so far I feel better than before the infusion. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. These lists dont include all possible side effects. 12 Medicines That Could Help, List Venofer Vial side effects by likelihood and severity. I used to get a different type but my . Some people are simply allergic to an active ingredient in the medication, so the body responds undesirably. Undergoingcancer treatmentwithradiation therapyorchemotherapy drugsmay result inhair loss, which can be devastating to somepeople. If you have a severe allergic reaction to Injectafer after youve left the medical facility where you received your dose of the drug, call your doctor right away. For example, if someone takes 100 mg of a drug, only half of it will be in the bloodstream in a couple ofhours. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. Injectafer and Feraheme are both brand-name drugs. Call your doctor for medical advice about side effects. If these effects continue or worsen, tell your doctor. Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. Here we look at how Injectafer and Feraheme are alike and different. You can also write a reminder on your calendar. With this condition, you also have a low hemoglobin level. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. If either is present, do not use the liquid. Venofer 100 mg iron/5 mL intravenous solution, Venofer 50 mg iron/2.5 mL intravenous solution, Venofer 200 mg iron/10 mL intravenous solution, Select a condition to view a list of medication options. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Also, keep in mind that if your anemia is causing certain symptoms, treatment with Injectafer may help those symptoms go away. Phosphorus is an electrolyte that your body needs in order to make energy. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. This site is intended for use only by US patients. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. For more information and to find out if youre eligible for support, call 877-4-IV-IRON (877-448-4766) or visit the program website. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. For instance, those who are taking other medications or supplements as part of home remedies may continue to suffer from the ill effects of their new medication because they dontinteract. (A medication class describes a group of drugs that work in the same way.). Once inside your body, ferric carboxymaltose releases iron into your system. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. For reasons we dont fully understand, some peoples immune system gets over-activated when the drug enters their body. <> The following information is provided for clinicians and other healthcare professionals. (IV iron is absorbed by the body more rapidly than oral iron.) pain in the arms or legs. If youre wondering how longside effectslast, youll be happy to know they can last just a few hours. Learn more about the types of tests and treatment. Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. Usually, when drugs may cause an immune system reaction like this, its a concern with your first dose of the drug. Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight. The following information describes dosages that are commonly used or recommended. Some people may also experience skin irritation from the adhesive tape and other medical equipment used during the procedure. Selected from data included with permission and copyrighted by First Databank, Inc. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? endobj Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. Or your doctor may recommend that you change your eating habits to include more iron in your diet. You should not receive Venofer if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis. To make sure Venofer injection is safe for you, tell your doctor if you have: hemochromatosis or iron overload (the buildup of excess iron). Venofer intravenous: Uses, Side Effects, Interactions & Pill - RxList How Long Does An Acid Trip Last? [Doctor-Reviewed Guide] They have been a god send. No, you most likely wont take Injectafer long term. You will be watched closely by your doctor for 30 minutes after each dose. In clinical studies, Injectafer was effective in treating IDA in adults who either didnt improve with or had side effects from taking iron by mouth. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. But for other people, their anemia may come back after Injectafer treatment. The information provided is not intended to replace your healthcare provider's medical advice. Why is the range so wide? People who weigh 110 pounds (about 50 kilograms) or more will receive two separate Injectafer doses of 750 milligrams each. With anemia, you have a low level of red blood cells (RBCs) in your body. These side effects can range from being mild to severe. The Injectafer dosage your doctor prescribes will depend on your body weight. Serious side effects, which are explained in more detail below in Side effect details, include: You may wonder how often certain side effects occur with this drug. Do not start, stop, or change the dose of any drug without checking with your doctor. You will need to talk about the benefits and risks to you and the baby. Side effects: DayQuil can cause side effects such as drowsiness, dizziness, nausea, vomiting, and stomach upset. Venofer is given as an infusion into a vein. Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells. Your doctor will go over your Which tests can diagnose iron deficiency anemia? Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. Brand-name medications usually cost more than generics. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Injectafer should be stored between 68F to 77F (20C to 25C). experience severe side effects, please seek medical attention right away and notify the ordering physician. Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: People with IDA have low blood levels of hemoglobin. Back pain. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. Most people will metabolize medication by half every time it circulates the body. intense abdominal pain. Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland. Many patients with kidney disease cannot get enough iron from food and require injections. Allergic reactions typically occur the first time your body is exposed to a drug. What are the side effects of Venofer? If your symptoms or health problems do not get better or if they become worse, call your doctor. Venofer is used to treat iron deficiency anemia in people with kidney disease. But you dont necessarily need to eat these foods unless your doctor tells you to do so. Keep in mind that the risk of certain pregnancy-related problems can be increased if iron deficiency anemia (IDA) is left untreated. Call your doctor for medical advice about side effects. Your doctor will be able to see how Venofer is working by reviewing your blood tests. Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose. US residents can call their local poison control center at 1-800-222-1222. This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. Possibleside effectsareweight gainand suicidal thoughts. 2005 - 2023 WebMD LLC. FG Trade/E+ sia Getty Images But some people have a delayed allergic reaction to certain drugs. fluid retention, especially in your arms, legs, or feet, people who took Feraheme had their hemoglobin level increase, on average, by 1.38 grams per deciliter (g/dL), people who took ferric carboxymaltose had their hemoglobin level increase, on average, by 1.63 g/dL, having strange cravings to eat items that arent food, such as ice, people who took Injectafer had their hemoglobin level increase, on average, by 1.6 grams per deciliter (g/dL), people who kept taking iron by mouth had their hemoglobin level increase, on average, by 0.8 g/dL, people who took Injectafer had their hemoglobin level increase, on average, by 2.9 g/dL, people who took the other intravenous iron product had their hemoglobin level increase, on average, by 2.2 g/dL, people who took Injectafer had their hemoglobin level increase by an average of 1.1 g/dL, people who took Venofer had their hemoglobin level increase by an average of 0.9 g/dL, cannot tolerate or have shown a poor response to oral iron, or, have been diagnosed with chronic kidney disease (CKD) that is non-dialysis dependent. Diarrhea. The following lists contain some of the key side effects that may occur while taking Injectafer. Last reviewed . This includes people who: Usually, hypophosphatemia doesnt cause symptoms. Theyll likely have you stop taking the pills while youre using Injectafer. Tell your doctor if you are taking iron supplements or other iron-based oral medications, such as: This list is not complete. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. While the side effects that occur during treatment with these drugs are increasingly well-cataloged, the long-term side effects that may result from receiving these drugs are only beginning to be studied. chills difficulty with moving ear congestion or pain flushed, dry skin fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes But even if youre not at risk for the condition, your doctor may still monitor your phosphorus levels. Venofer treatment may be repeated if iron deficiency reoccurs. wAd**CgI%"nn{Oa[q{r5 This may be helped by giving the medication more slowly or at a lower dose. You may also need to monitor your blood pressure at home. In the second group, some people switched from taking iron by mouth to taking Injectafer. Best food forward: Are algae the future of sustainable nutrition? This medication is given by injection into a vein as directed by your doctor. Its possible to get rid of or reduce the severity ofside effects. These changes could help improve your anemia on a long-term basis. One class of immune checkpoint inhibitors targets the protein PD-1, which acts as a brake to keep the immune system in check. generalized weakness. Precautions. Venofer (iron sucrose): Basics, Side Effects & Reviews - GoodRx The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. Symptoms of overdosage include drowsiness, mental confusion, dizziness, diarrhea and vomiting etc. Some products that may interact with this drug include: vitamin products, other iron-containing products. I was surprised too but the Dr said it definitely sounds like a reaction. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Iron sucrose can make it harder for your body to absorb iron medications you take by mouth. Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. 3 0 obj Venofer is for use in adults and children at least 2 years old. You should not be treated with this medicine if you have ever had an allergic reaction to an iron injection. Depending on your doctors instructions and Cholesterolmedication may reduce the risk of a stroke but it can decrease the quality of life for some people but causingweight gain, dizziness, nausea, and musclepain. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. Someside effectsare temporary or last as long as the person continues takingprescription medicine. With IDA, you have anemia (low red blood cell level) thats due to not having enough iron in your body. Some people only need one treatment course of Injectafer. For people weighing 50 kg (about 110 lb) or more, administer Injectafer in two doses of 750 mg, at least 7 days apart. Review our medical disclaimer. Its caused by your body not having enough iron, which is needed to make hemoglobin. Procedure Details Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. If youre not sure if youll need to get prior authorization for Injectafer, contact your insurance company. Some may be a better fit for you than others. This survey is being conducted by the WebMD marketing sciences department. Together, you and your doctor can develop a treatment plan thats best for you. With IV infusion, the drug is given as a slow drip into your vein over a period of time. Dating an Addict in Recovery: What to Expect In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. Should I avoid certain foods while taking Venofer Vial? <> Venofer may reduce the absorption of iron preparations taken by mouth. TheNational Instituteof Health (NIH) and the U.S. Food andDrug Administration(FDA) monitor theside effectsof new and approved medications to ensure safety. For additional information, contact your healthcare provider. These side effects may include constipation and diarrhea. These people may lose weight as their anemia improves because theyre more active. 2023 Medicine.com All rights reserved. For information on Injectafers effectiveness in treating IDA, see the Injectafer Uses section below. The researchers looked to see how well each drug worked to increase peoples hemoglobin level. This information is not specific medical advice and does not replace information you receive from the healthcare provider. This treatment course is split into two doses of the drug, which are given at least 7 days apart. Sharing this information can help you avoid potential interactions. Its because everyones body is different. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. Details. However, diarrhea it isnt very common in people using Injectafer. With IDA, you have low hemoglobin levels. muscle pain. This is only a brief summary of general information about this medicine. Talk with your doctor. Injectafer is a brand-name prescription drug. For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. Your doctor will recommend whether you should stop taking your multivitamin or any other supplements. Brandon ColbyMD, a medical expert specializing in preventive medicine and clinicalgenomics. Also tell them about any vitamins, herbs, and supplements you use. Any long-term side effects/dangers from iron infusions? With slow IV injection, the drug is given as a single, slow injection into your vein. All of the people took iron by mouth for 2 weeks. signs of inflammation in the lining of your stomach --pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. Depending on your anemia symptoms, your weight changes may be different than those described here. pain or burning at the injection site. There are different types of anemia, but IDA is the most common type. Nose or throat irritation. It belongs to a class of medications called iron replacement products. For more information about Injectafers approved uses, see the section Injectafer uses below. In this study, compared with their level before treatment: Injectafer isnt currently approved for use in children. Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. The Food and Drug Administration (FDA) approves prescription drugs such as Injectafer to treat certain conditions. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Both Injectafer and Feraheme belong to a class of medications known as iron replacement products. Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. You will need frequent medical tests to help your doctor determine how long to treat you with Venofer. People who weigh less than 110 lb (about 50 kg) will receive two separate Injectafer doses of 15 mg/kg of body weight. Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. I can't take oral supplements because they cause horrible debilitating Constipation. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. You should not receive Venofer if you have known allergies to iron sucrose. If you are breastfeeding, tell your doctor if you notice diarrhea or constipation in the nursing baby. Both Injectafer and Venofer belong to a class of medications called iron replacement products. If a person does not have an allergic response or any other unanticipated reactions, a doctor will administer the remaining iron. If you have questions about using Injectafer for anemia during pregnancy, talk with your doctor. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. treatment schedule in further detail. If you are using this medication at home, learn all preparation and usage instructions from your health care professional. You may also report side effects at https://www.fda.gov/medwatch. IQVIA [NSP Audit from MAT November 2013 to November 2018]. The drug helps increase your hemoglobin level back to a value thats within the normal range. upper respiratory infection. Generics tend to cost less than brand-name drugs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Feraheme is also approved to treat IDA in adults who either didnt have improvement in their IDA or had side effects with iron treatment thats taken by mouth. It can also cause skin irritation and redness. What is Venofer? * Feraheme has a boxed warning for this side effect. People with IDA have low blood levels of hemoglobin. Venofer (iron sucrose) dosing, indications, interactions, adverse The benefit of treating your condition during pregnancy may outweigh any risks. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. Its not known if Injectafer is safe to use during pregnancy. Tell your doctor about the allergy and what signs you had. Storage Condition Store in a cool and dry place protected from light. Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. Although a single administration of FCM frequently causes transient hypophosphatemia, a 2016 study showed that repeated treatment with FCM is associated with a high risk of developing severe and prolonged hypophosphatemia and should therefore be monitored. It is given into a vein for a period of time. A delayed reaction can occur in two different ways: It can happen hours or days after you receive a drug, or it can happen after a second (or later) dose of a drug. Both of theseside effectscould worsen depression and lead tolife-threateningconsequences. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. Learn more about these, as well as the symptoms, diagnosis, and treatments. Talk with the doctor. These pregnancy-related problems include preterm delivery and low birth weight of your infant. Find comprehensive medical information for Venofer intravenous on RxList including its uses, side effects, precautions, drug interactions, overdose, pill images & warnings . Tell your doctor if you are taking iron supplements or other iron-based oral medications. This medication is given by injection into a vein as directed by your doctor. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. 2022 American Regent, Inc.PP-VE-US-0016 (v6.0)1/2022, Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your organs and tissues through hemoglobin, If you or your child has been prescribed Venofer, its based on your blood work, which shows how many red blood cells you have and whether you have enough iron in your blood cells, If you are iron deficient, raising your iron levels can help increase your hemoglobin levels, Treating your anemia may help prevent future health problems, Over time, untreated IDA can cause heart problems; if you already have heart problems, it can make those problems worse, Venofer is given intravenously (through an IV) and <> The infusion concentration should not be less than 2 mg of Injectafer per mL of solution. Keep in mind that there may be additional costs related to getting your doses of the drug at a medical facility. Iron Infusion: Benefits, Side Effects, and What to Expect - Healthline Dilute Venofer in a maximum of 250 mL of 0.9% NaCl. This may lead to the person needing a higher dose compared to someone who is muchsmaller.